What is the TAME clinical trial?
— The TAME clinical trial is a study that aims to investigate the potential anti-aging effects of metformin and determine if it can extend lifespan and reduce all-cause mortality in older individuals.
What are the potential benefits of metformin?
— Metformin has shown potential in protecting against diabetes and improving outcomes in individuals with mild cognitive impairment, based on small clinical studies.
What is the primary focus of the TAME trial?
— The TAME trial focuses on the overall anti-aging effects of metformin, being agnostic of specific diseases.
Can metformin target aging even if started later in life?
— Yes, studies have shown that metformin can still target aging even if started later in life, as aging continues to progress even after the onset of disease.
What outcomes are considered important in the TAME trial?
— The TAME trial considers various health outcomes such as cardiovascular events, cancer occurrences, cognitive decline, mortality, and health span issues like frailty and hip fractures.
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